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The selection indicates that a combination of being female, a non-smoker, and the use of opioids suggests a decreased chance of postoperative nausea and vomiting (PONV). This is grounded in the understanding that certain demographic and lifestyle factors, along with medications used during and after surgery, can influence PONV outcomes.

Being female is commonly associated with an increased risk of PONV, while being a non-smoker is generally associated with a decreased risk. Smoking has been found to have a protective effect against PONV, likely due to the effects of nicotine on the central nervous system and its role in gastrointestinal motility. The use of opioids, although they can increase the likelihood of nausea, in this context, does not overshadow the protective factors of the other two conditions.

In summary, the combination of being a non-smoker and the analysis of the demographic factors helps to clarify why the elements argued in this choice contribute to a decreased chance of experiencing PONV, in contrast to the potential risk factors presented in the other options.